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Vraag gesteld door: Windy - 4 weken geleden

Leg mij uitgebreid het volgende onderwerp uit: Rationale: This initiative is focused on building a global consensus around core diagnostic criteria for
malnutrition in adults in clinical settings.
Methods: In January 2016, the Global Leadership Initiative on Malnutrition (GLIM) was convened by
several of the major global clinical nutrition societies. GLIM appointed a core leadership committee and a
supporting working group with representatives bringing additional global diversity and expertise.
Empirical consensus was reached through a series of face-to-face meetings, telephone conferences, and
e-mail communications.
Results: A two-step approach for the malnutrition diagnosis was selected, i.e., first screening to identify at
risk status by the use of any validated screening tool, and second, assessment for diagnosis and grading
the severity of malnutrition. The malnutrition criteria for consideration were retrieved from existing
approaches for screening and assessment. Potential criteria were subjected to a ballot among the GLIM
core and supporting working group members. The top five ranked criteria included three phenotypic
criteria (non-volitional weight loss, low body mass index, and reduced muscle mass) and two etiologic
criteria (reduced food intake or assimilation, and inflammation or disease burden). To diagnose malnutrition at least one phenotypic criterion and one etiologic criterion should be present. Phenotypic metrics
for grading severity as Stage 1 (moderate) and Stage 2 (severe) malnutrition are proposed. It is recommended that the etiologic criteria be used to guide intervention and anticipated outcomes. The recommended approach supports classification of malnutrition into four etiology-related diagnosis categories.
Conclusion: A consensus scheme for diagnosing malnutrition in adults in clinical settings on a global scale is
proposed. Next steps are to secure further collaboration and endorsements from leading nutrition professional societies, to identify overlaps with syndromes like cachexia and sarcopenia, and to promote dissemination, validation studies, and feedback. The diagnostic construct should be re-considered every 3e5 years.
2018 Elsevier Ltd, European Society for Clinical Nutrition and Metabolism and American Society for
Parenteral and Enteral Nutrition De uitleg moet geschreven zijn op het niveau van de Universiteit.

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